• To explain the whys and wherefores of the signs and symptoms of the patients.
• Providing a sound foundation for rational clinical care and therapy.
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Sir William Osler 1849-1919
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基础医学课目中与临床最接近 的当推病理学，因为它是临床与基 础之间的桥梁，要学好临床先要学 好病理学，我毕业后才认识这个道 理。原想加学一年病理学以资祢补， 可是没能做到，至今引为遗憾。
—— 著名医学家张孝骞
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结束语
当你尽了自己的最大努力时，失败也是伟大的， 所以不要放弃，坚持就是正确的。
practice • The important step in evidence-based medicine • The functional consequences of the morphologic
changes (clinical significance)
4
Pathology
• Biopsy
When You Do Your Best, Failure Is Great, So Don'T Give Up, Stick To The End
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谢谢大家
荣幸这一路，与你同行
It'S An Honor To Walk With You All The Way
演讲人：XXXXXX
时 间：XX年XX月XX日
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Introduction to pathology
• A bridging discipline involving both basic science and clinical practice.
• Devoted to the study of the structural and functional changes in cells, tissues and organs that underlie disease.
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Etiology
• Intrinsic or genetic • Acquired
infectious nutritional chemical physical
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Pathogenesis
• Initial stimulus --------> ultimate expression of disease
Histopathology
• Cytology
Electromicroscopy
• Resected specimens Histochemistry
• Autopsy
Microbiology
• Cell & tissue culture
• immunohistochemistry
• Molecular pathology
Textbook
Pathology
Second Edition Editor in chief: CHEN Jie and LI Gandi
People’s Medical Publishing House
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Introduction to pathology
Peking Union Medical College Chen Jie
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Clinical significance
• Functional abnormality • Clinical features
(symptoms and signs) • Clinical course • Prognosis of the disease
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“As is our pathology, so is our medicine” “病理为医之本”
• Defective gene --------> cysts and fibrosis
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Morpቤተ መጻሕፍቲ ባይዱologic changes
• Structural alterations cells tissues organs
• Characteristic of the disease • Diagnostic of the etiologic process
Pathology
• The study of etiology of the disease • The study of pathogenesis of disease • The study of morphological changes of disease • The most important diagnosis in modern medical