神经内科英文课件-脑囊虫病
leg, and shoulder muscles .
Treatment and prevention
• The usual dose of praziquantel is 50 mg/kg of body weight, given orally daily for 1 5 to 30 days. Albendazole (5 mg/kg tid for 15 to 30 days), an alternative treatment, is believed by some to be more effective.
Cerebral Cysticercosis 脑囊虫病
• In the central and south America and in parts of Africa and the Middle East,south-east Asia.
• This is the larval or intermediate stage of infection with the pork tapeworm T. Solium.
• Initially, treatment may seem to exacerbate neurologic symptoms, with an increase in cells and protein in the CSF.corticoid and mannitol may be useful.
2 subarachnoid space type:headache,hydrocephalus,meningi
3 intraventricle type:Brun’s sign middle foramen of the four ventricle
4 spinal cord type.
Laboratory findings
• The serum antibody to cyst worm is usually positive using ELISA or Western blot.
• CSF:normal;lymphocyte,pressure,protein increase • CT,MRI:contrast-enhanced mass lesions with
• affects the brain in 60~90%of cases
Pathogenesis
Food contaminated by eggs of T. solium.
Retrograde infection of proglottid
Anus to oral
Onchosphere in duodenum
All over the bysticercus cellclosae
Clinical manifestation
1 cerebral parenchyma type:seizures,focal signs,encephalitis
neurologic
surrouding edema,intracerebral calcification,ventricular enlargement.
Diagnosis
• History • CT,MRI • antibody • the presence of multiple calcified lesions in the thigh,
• Surgery