[4]M ehd i zade A,Lovb l ad KO,W il hel m KE,et al.Rad i ation dose inverteb rop l ast y[J].Neu rorad i ology,2004,46(3):243-245.[5]Dera mond H,W right NT,Belkoff S M.T e mperat u re elevati oncaused by bone ce m en t pol y m eri zation du ri ng vert eb rop lasty[J].Bon e,1999,25(Suppl2):17S-21S.[6]N agana w a S,N i has h i T,Fukats u H,et a l.Pre-s u rgicalm app i ng ofp ri m ary m otor cortex by f unctionalM RI at3T:effects of i ntravenousad m i n istration of Gd-DTPA[J].Eu r R ad i o,l2004,14(1):112-114.[7]罗奋棋.经皮椎体成形术临床治疗进展[J].福建医药杂志,2008,30(3):87-90.[8]N iW F,Ch iYL,L i n Y,et al.The class i fi cati on and i ts cli n ical va-lue for extraverteb ral ce m en t l eakage co m p li cated by p ercutaneousverteb ral augm entation[J].Zhonghua W ai K e Za Zh,i2006,44(4):231-234.[9]Choe D H,M arom EM,Ahrar K,et a l.Pu l m onary e m bolis m of pol y-m et hyl m ethacrylate duri ng percu t an eou s vert eb rop l asty and ky-phop lasty[J].Am J Roen t geno,l2004,183(4):1097-1102. [10]Trou tAT,Kall u es DF,Kau f m ann TJ.Ne w fract u res after vertero-p l asty[J].Am J N eurorad io,l2006,27(1):217-223.[11]Upp i n AA,H irsch J A,C entenera L V,e t al.Occurrence of ne w ver-tebral body fract u re after percutan eous vertebroplasty in pati en tsw it h osteoporosis[J].R ad i ol ogy,2003,226(1):119-124.[12]G rados F,Dep ri ester C,C ayrolle G,e t al.Long t er m ob servati ons ofverteb ral os t eoporotic f ract u res treated by percutan eous vertebro-p l asty[J].Rheum at o l ogy(Oxford),2000,39(12):1410-1414.[13]M onti celliF,M eyer H J,Tutsch-Bauer E.Fatal pu l m onary ce m en te mboli s mf o ll o w i ng percu taneou s vertebrop l ast y(P VP)[J].Foren-sic S ci In t,2005,149(1):35-38.[14]L i m SH,K i m H,K i m HK,et al.M u l ti p l e card i ac perf orati on s andpu l m onary e m boli s m caused by ce m en t leakage after p ercutaneousvertebroplast y[J].Eu r J Card i othorac Surg,2008,33(3):509-511.[15]王东来,冯建刚.经皮椎体成形术并发脊髓梗死1例报告[J].中华脊柱脊髓杂志,2008,18(5):376.[16]C hoe D H,M aro m EM,Ahrar K,et a l.Pu l m onary e m bolis m of pol y-m ethyl m et hacryl ate du ri ng percutaneous verteb rop l ast y and ky-phop l asty[J].Am J Roentgeno,l2004,183(4):1097-1102. [17]Bel koff SM,M at h is J M,Jas per LE,e t a l.Th e b i o m echan i cs of ver-t eb rop l asty-t he effect of ce m ent vol um e on m ech an i cal beh avi or[J].S pi n e,2001,26(14):1537-1541.[18]H itchon P W,G oelV,Drak e J,e t paris on of t h e b io m echan-i cs of hydroxyapatite and pol y m et hy l m ethacrylate vertebroph sty i n acadaveric s p i nal co m p ress i on fract u re m ode1[J].J N euros u rg,2001,95(Suppl2):215-220.[19]Perry A,M ah ar A,M ass i e J,et a l.B io m echan ical evaluati on of ky-phop l asty w i th cal ci um s u lfate ce m ent i n a cadaveri c osteoporoti cvertebra l co m pression fract u re m ode1[J].Sp i ne,2005,5(5):489-493.[20]D i a m ond TH,Bryan tC,Brown e L,et a l.C li n ical outco m es after a-cu te osteoporotic verteb ral frat u res:a2-year non-rando m i sed trialco mpari ng PVP w i th conservati ve therapy[J].M ed J Au st,2006,184(3):113-117.[21]杨祚璋,许建波等。
脊柱转移癌经皮椎体成形术联合125I粒子植入治疗[J]。
中华放射医学与防护杂志,2006,26(2):178-179.[22]Dean J R,Is on KT,G iss hen P.Th e s trengt h en i ng effect of percuta-neuou s vertebrop l ast y[J].C li n Rad i o,l2000,55(6):471-476. [23]张长江,任文杰.经皮椎体成形术治疗脊柱转移肿瘤的价值[J].中国骨肿瘤骨病,2008,7(3):167-170.收稿日期:2008-10-6修回日期:2008-12-15癌症恶病质的综合性治疗进展邱正国v(综述),陈思曾(审校)(福建医科大学附属第一医院普外科,福州350004)中图分类号:R730.6文献标识码:A文章编号:1006-2084(2009)03-359-05摘要:癌症恶病质(CC)是恶性肿瘤患者晚期常见的临床综合征之一。
其病因、发病机制相当复杂,多种细胞因子和代谢物质都在CC的发生、发展中起重要影响,针对这些因素的治疗是目前的关注点。
CC的治疗涉及营养补充、药物治疗、中医治疗、心理治疗等多方面的综合性治疗。
现就CC目前的治疗手段和防治对策予以综述。
关键词:癌症恶病质;细胞因子;综合治疗Comprehensive Treat m ent Prog res s in C ancer Cachex i a QIU Zheng-gu o,C HEN S i-ze ng.(D e part m ent of Genera l Surg e ry,t h e F irstH os p italAff ili a te d t o Fujian M e d ic a l Un i versit y,Fu zhou350004,Ch i na) Abstract:C ancer cach exi a(CC)is on e of cli n i c synd ro m es for m ali gnant tu m or pati en ts i n advanced stage.The eti op athogen i s i s and pat hogen esy are very co mp lex,wh ich as soci ated w ith mu c h cytok i ne and m etaboli n.The recent focu s is on thes e fact ors t o relieve CC.The treat m ent refer t o co m preh ens i ve m et hods, s u ch as nu triti onal supple m ent,phar m acy i nterventi on,traditi onal C hinese m ed ici ne and psychotherapy.The arti cle sa mm ari zes,t h e p reasent treat m en tm et hod and p reventi on m eas u res to CC.K ey words:C ancer cachex i a;C yt ok i ne;C o m prehen sive treat m ent癌症恶病质(cancer cachex ia,CC)主要是由肿瘤的一些产物及机体释放的细胞因子引起的以全身代谢紊乱为特征的一种继发性反应的临床综合征。