1. Single Step92%OverviewSteps/StagesNotes
1.1R:NH3, R:H2O, S:H2O
Reactants: 1, Reagents: 2, Solvents: 1, Steps:
1, Stages: 1, Most stages in any one step: 1
ReferencesAmmonolysis of cyclic aromatic acid imidesBy Arkhipova, I. A. et alFrom Zhurnal Organicheskoi Khimii, 27(3),621-8; 1991
CASREACT ®: Copyright © 2016 American Chemical Society. All Rights Reserved. CASREACT contains reactionsfrom CAS and from: ZIC/VINITI database (1974-1999) provided by InfoChem; INPI data prior to 1986; Biotransformationsdatabase compiled under the direction of Professor Dr. Klaus Kieslich; organic reactions, portions copyright 1996-2006John Wiley & Sons, Ltd., John Wiley and Sons, Inc., Organic Reactions Inc., and Organic Syntheses Inc. Reproducedunder license. All Rights Reserved.
2. Single Step
81%OverviewSteps/StagesNotes
1.1R:NH3, S:H2O, 24 h, rt
literature preparation, Reactants: 1, Reagents:
1, Solvents: 1, Steps: 1, Stages: 1, Moststages in any one step: 1
ReferencesONSH: Optimization of OxidativeAlkylamination Reactions through Study ofthe Reaction Mechanism
By Verbeeck, Stefan et alFrom Journal of Organic Chemistry, 75(15),5126-5133; 2010
Experimental Procedure
SciFinder®Page 1 1H NMR (DMSO-d6): δ 7.69 (s, 2H), 7.43-7.49 (m, 4H), 7.31 (s, 2H). 13C NMR (DMSO-d6) δ: 170.7,136.7, 129.7, 128.1. HRMS (ESI) for C8H9N2O2+ [M + H]+ , calcd 165.0659, found 165.0645.
CASREACT ®: Copyright © 2016 American Chemical Society. All Rights Reserved. CASREACT contains reactionsfrom CAS and from: ZIC/VINITI database (1974-1999) provided by InfoChem; INPI data prior to 1986; Biotransformationsdatabase compiled under the direction of Professor Dr. Klaus Kieslich; organic reactions, portions copyright 1996-2006John Wiley & Sons, Ltd., John Wiley and Sons, Inc., Organic Reactions Inc., and Organic Syntheses Inc. Reproducedunder license. All Rights Reserved.
3. Single Step
81%OverviewSteps/StagesNotes
1.1R:NH3, S:H2O, 24 h, rt
literature preparation, Reactants: 1, Reagents:
1, Solvents: 1, Steps: 1, Stages: 1, Moststages in any one step: 1
ReferencesONSH: Optimization of OxidativeAlkylamination Reactions through Study ofthe Reaction Mechanism
By Verbeeck, Stefan et alFrom Journal of Organic Chemistry, 75(15),5126-5133; 2010
CASREACT ®: Copyright © 2016 American Chemical Society. All Rights Reserved. CASREACT contains reactionsfrom CAS and from: ZIC/VINITI database (1974-1999) provided by InfoChem; INPI data prior to 1986; Biotransformationsdatabase compiled under the direction of Professor Dr. Klaus Kieslich; organic reactions, portions copyright 1996-2006John Wiley & Sons, Ltd., John Wiley and Sons, Inc., Organic Reactions Inc., and Organic Syntheses Inc. Reproducedunder license. All Rights Reserved.
4. Single Step
OverviewSteps/StagesNotes
SciFinder®Page 2 1.1R:NH
3
Reactants: 1, Reagents: 1, Steps: 1, Stages:
1, Most stages in any one step: 1
ReferencesPhthalocyanine green pigment fine cleanproduction process
By Yang, Hanzhou and Zhu, JiFrom Faming Zhuanli Shenqing, 104804465,29 Jul 2015
CASREACT ®: Copyright © 2016 American Chemical Society. All Rights Reserved. CASREACT contains reactionsfrom CAS and from: ZIC/VINITI database (1974-1999) provided by InfoChem; INPI data prior to 1986; Biotransformationsdatabase compiled under the direction of Professor Dr. Klaus Kieslich; organic reactions, portions copyright 1996-2006John Wiley & Sons, Ltd., John Wiley and Sons, Inc., Organic Reactions Inc., and Organic Syntheses Inc. Reproducedunder license. All Rights Reserved.
5. Single Step
OverviewSteps/StagesNotes1.1Reactants: 1, Steps: 1, Stages: 1, Most stagesin any one step: 1
ReferencesSynthesis and hypolipidemic activity of 3-imino-1-oxoisoindolines in rodents
By Murthy, Akula R. K. et alFrom Pharmaceutical Research, 4(1), 21-7;1987
CASREACT ®: Copyright © 2016 American Chemical Society. All Rights Reserved. CASREACT contains reactionsfrom CAS and from: ZIC/VINITI database (1974-1999) provided by InfoChem; INPI data prior to 1986; Biotransformationsdatabase compiled under the direction of Professor Dr. Klaus Kieslich; organic reactions, portions copyright 1996-2006John Wiley & Sons, Ltd., John Wiley and Sons, Inc., Organic Reactions Inc., and Organic Syntheses Inc. Reproducedunder license. All Rights Reserved.
SciFinder®Page 3