机理参考文献
表征单萜对膜的作用1binding to LPS23Ag的作用机理4壳聚糖作用机理5Hypoxis rooperi corm extract对膜的作用67 peptide 荧光法，Confocal microscopy，lipid vesicle titration test8
Flow cytometry analysis, using liposome and membrane probe 9
Lipid binding and membrane penetration10H谱及P谱研究peptide与菌膜的作用11-121314-15 1. Trombetta, D.; Castelli, F.; Sarpietro, M. G.; Venuti, V.; Cristani, M.; Daniele, C.; Saija, A.; Mazzanti, G.; Bisignano, G., Mechanisms of antibacterial action of three monoterpenes. Antimicrobial Agents and Chemotherapy 2005, 49, (6), 2474-2478.
2. Tsubery, H.; Yaakov, H.; Cohen, S.; Giterman, T.; Matityahou, A.; Fridkin, M.; Ofek, I., Neopeptide antibiotics that function as opsonins and membrane-permeabilizing agents for gram-negative bacteria. Antimicrobial Agents and Chemotherapy 2005, 49, (8), 3122-3128.
3. Rosenfeld, Y.; Sahl, H. G.; Shai, Y., Parameters involved in antimicrobial and endotoxin detoxification activities of antimicrobial peptide. Biochemistry 2008, 47, (24), 6468-6478.
4. Jung, W. K.; Koo, H. C.; Kim, K. W.; Shin, S.; Kim, S. H.; Park, Y. H., Antibacterial activity and mechanism of action of the silver ion in Staphylococcus aureus and Escherichia coli. Applied and Environmental Microbiology 2008, 74, (7), 2171-2178.
5. Raafat, D.; von Bargen, K.; Haas, A.; Sahl, H. G., Insights into the mode of action of chitosan as an antibacterial compound. Applied and Environmental Microbiology 2008, 74, (12), 3764-3773.
6. Laporta, O.; Funes, L.; Garzon, M. T.; Villalain, J.; Micol, V., Role of membranes on the antibacterial and anti-inflammatory activities of the bloactive compounds from Hypoxis rooperi corm extract. Archives of Biochemistry and Biophysics 2007, 467, (1), 119-131.
7. El Amri, C.; Lacombe, C.; Zimmerman, K.; Ladram, A.; Amiche, M.; Nicolas, P.; Bruston, F., The plasticins: Membrane adsorption, lipid disorders, and biological activity. Biochemistry 2006, 45, (48), 14285-14297.
8. Lee, D. G.; Kim, D. H.; Park, Y.; Kim, H. K.; Kim, H. N.; Shin, Y. K.; Choi, C. H.; Hahm, K. S., Fungicidal effect of antimicrobial peptide, PMAP-23, isolated from porcine myeloid against Candida albicans. Biochemical and Biophysical Research Communications 2001, 282, (2), 570-574.
9. Sung, W. S.; Park, Y.; Choi, C. H.; Hahm, K. S.; Lee, D. G., Mode of antibacterial action of a signal peptide, Pep(27) from Streptococcus pneumoniae. Biochemical and Biophysical Research Communications 2007, 363, (3), 806-810.
10. Katz, M.; Tsubery, H.; Kolusheva, S.; Shames, A.; Fridkin, M.; Jelinek, R., Lipid binding and membrane penetration of polymyxin B derivatives studied in a biomimetic vesicle system. Biochemical Journal 2003, 375, 405-413.
11. Ouellet, M.; Doucet, J. D.; V oyer, N.; Auger, M., Membrane topology of a 14-mer model amphipathic peptide: A solid-state NMR spectroscopy study. Biochemistry 2007, 46, (22), 6597-6606.
12. Gehman, J. D.; Luc, F.; Hall, K.; Lee, T. H.; Boland, M. P.; Pukala, T. L.; Bowie, J. H.; Aguilar, M.
I.; Separovic, F., Effect of antimicrobial peptides from Australian tree frogs on anionic phospholipid membranes. Biochemistry 2008, 47, (33), 8557-8565.
13. Bonev, B. B.; Chan, W. C.; Bycroft, B. W.; Roberts, G. C. K.; Watts, A., Interaction of the lantibiotic nisin with mixed lipid bilayers: A P-31 and H-2 NMR study. Biochemistry 2000, 39, (37), 11425-11433.
14. Pukala, T. L.; Boland, M. P.; Gehman, J. D.; Kuhn-Nentwig, L.; Separovic, F.; Bowie, J. H., Solution structure and interaction of cupiennin 1a, a spider venom peptide, with phospholipid bilayers.
Biochemistry 2007, 46, (11), 3576-3585.
15. Papo, N.; Shai, Y., New lytic peptides based on the D,L-amphipathic helix motif preferentially kill tumor cells compared to normal cells. Biochemistry 2003, 42, (31), 9346-9354.。