默克密理博纳米微球和Multiplex技术在临床诊断中的应用
西安2011年3月10日
Subline Arial 16pt
Estapor®technology and business overview Estapor®技术及业务介绍
R. Vidal
March, 10-12, 2011
Business Plan -Confidential
Conditioning/packaging Analytics Production R&D preparations 研发制备
Heterogeneous 非均匀介质
Water soluble initiator
水溶性引发剂
Diameter 亚微米级粒径
surfactant
i nitiator
Polymer particle
Initiator radical
Surfactant
nucleus
polymerization
oligomer
Monomer
WATER AIR 空气
Monomer reservoir
Initiator
Unentered micelle
COOH COOH
COOH
X X -COOH, -OH, -NH 2,H …）
1 μm 6 μm
N
Applications
product
产品线及主要应用
ISO-9001认证的微球研发和生产体系
Other applications: Confocal Microscopy, Biosensors, Biochips, BioCatalysis, Microfluidics, Multiplexing, Immunoprecipitation, Mass Spectro, Agro-food but also Electronics, Cosmetics, Traceability….
其他应用：共聚焦显微镜，生物传感器，生物芯片，生物催化，微流控技术，多因子检测，免疫沉淀，质谱，农产食品以及电子，化妆品等
选择被动吸附还是共价偶联？减少非特异性结合，改善信噪比
Physical adsorption
Side
up
Covalent binding
Covalent binding
Covalent binding
Esterification
Covalent binding
ThioEther
Covalent binding
Hydrazone basis
Covalent binding
Covalent binding
Amine bound Covalent binding
Amine bound
Hydrophobic Hydrophilic Amine bound
Bio-binding ۞۞Streptavidin
Anti-IgG
۝۝Protein
need to be washed before they can be used, but this is not
: to maximize effectiveness of the EDC reaction we studied a number of conditions using
We can easily use different colours of dyed microspheres.读取更加快速、简便、准确。

We call this:
The Fluorescent Beads,
The MICTSystems, 。