Introduction to PsychologyDr. Paul Bloom Lecture 2 Foundations: This is Your BrainNobel Prize winning biologist Francis Crick“The Astonishing Hypothesis” is summarized like this:You, your joys and your sorrows, your memories and your ambitions, your sense of personal identity and free will are in fact no more than the behavior of a vast assembly of nerve cells and their associated molecules.As Lewis Carroll’s Alice might have phrased it: “You’re nothing but a pack of neurons”.（你不过是一堆神经元罢了）Most people are dualists. Dualism is a very different doctrine. It’s a doctrine that can be found in every religion and in most philosophical systems throughout history.Plato（柏拉图）Philosopher Rene Descarts (勒奈.笛卡尔) explicitly asked a question “Are human merely physical machines, merely physical things?” And he answered “No”.He agreed that animals are machines, but people are different. There’s a duality of people. Like animals, we possess physical material bodies, but unlike animals, what we are is not physical. We’re immaterial souls that possess physical bodies. The claim is for humans at least, there are two separate things, there’s our material bodies and there’s our immaterial minds.Descarts made two arguments for dualism:One argument involved observations of a human action. Humans are not limited to reflexive action. Rather humans are capable of coordinated, creative, spontaneous things. We can use language, for instance. We can choose what we want to say, and machines can’t.The second argument is quite famous and this he came to use method of doubt.He started to ask a question, what can I be sure of ? And he said, well, I believe there’s a God, but honestly I can’t be sure there’s a God. I believed I lived in a rich country, but maybe I’ve been fooled”. He even said, I believe I have had friends and family but maybe I am being tricked. He even doubt that whether he has a body.But He concluded that he can’t doubt that he is himself thinking. There is something really different about having a body, there’s always uncertain, from having a mind. He used this to support that bodies and minds are separate.And so he concluded, I knew that I was a substance, the whole essence or nature of which is to think and that for its existence, there is no need of any place nor does it depend on any material thing. That is to say, the soul by which I am, what I am, is entirely distinct from body.I want to illustrate the common sense nature of this in a few ways:One thing is our dualism is enmeshed in our language, so we have a certain mode of talking about things that we own or things that are closed to us. We talk about owning our brains as if we’re somehow separate from them.Our dualism shows up in intuitions about personal identity. This means that common sense tells us that somebody can be the same person even if their body undergoes radical and profound changes.Franz Kafka:（卡夫卡）ᯛAs Gregor Samsa woke one morning from uneasy dreams, he found himself transformed in his bed into a gigantic insect.”Homer (荷马) described the fate of the companions of Odysseus（奥德赛）who were transformed by a witch into pigs.One analysis of multiple personality disorder is that you have many people inside a single body fighting it out for control.Common sense tells us you could have more than one person inside a single body.Most people believe that people can survive the destruction of their bodies. Now, cultures differ according to the fate of the soul. Some cultures have the body going to Heaven or descending to hell. Others have you occupying another body. Still, others have you occupying an amorphous spirit world. But what they share in the idea that what you are is separable from this physical thing you carry around and the physical thing that you carry around can be destroyed while you live on.As Crick pointed out the scientific consensus now is the dualism is wrong. There is no “you” separable or separate from your body. In particular, there is no “you” separable from your brain. To put in the way cognitive scientists and psychologists and neuroscientists like to put it, “the mind is what the brain does.” The mind reflects the working of the brain just like computation reflects the working of a computer.The reasons for supporting this view:One reason is dualism has always had its own problems. For one thing, it’s a profoundly unscientific doctrine. We want to know as curious people how children learn language, what we find attractive or unattractive, what’s the basis for mental illness. And dualism simply says, “It’s all nonphysical, it’s part of the ether” and hence fails to explain it. More specifically, dualists struggle to explain how a physical body connects to an immaterial soul. What’s the conduit?Now we know physical bodies can do complicated and interesting things, and this opens to a possibility that humans are physical things, in particular, that humans are brains.Finally, there is strong evidence that the brain is involved in mental life. What’s new is we can now in different ways see the direct effects of mental life.The scientific consensus is that all of mental life including consciousness and emotions and choice and morality are the products of brain activities.The brain is grey, when you take it out of the mind, it’s called grey matter.The neurons, the basic building blocks of the thought, combine to other mental structures and into different subparts of the brain and finally to the whole thing.So, one of the discoveries of psychology is that the basic unit of the brain appears to be the neuron. The neuron is a specific sort of the cell and the neuron has three major parts.There are the dendrites, these little tentacles here. And the dendrites get signals from other neurons, there signals can be either excitatory which is that they raise the likelihood the neuron will fire or inhibitory in that they lower the likelihood that the neuron will fire. And it fires along the axon. The axon is much longer than the dendrites. Surrounding the axon is the myelin sheath, which is actually just insulation. It helps the firing work quicker.Some facts about neurons:There are a lot of them, about one thousand billion of them and each neuron can be connected to around thousands, perhaps tens of thousand, other neurons.Neurons come in three flavors. There are sensory neurons, which take information from the world. So when you see me, for instance, there are neuronsfiring from you retina sending signals to your brain. There are motor neurons. If you decide to raise your hand, those are motor neurons telling the muscles what to do. And there are interneurons which connect the two. And basically, the interneurons do the thinking. They make the connection between the sensation and action. There are parts of the brain in which neurons can re-grow.One interesting thing about the neurons is a neuron is like a gun. It either fires or it doesn’t. It’s all or nothing. If you squeeze the trigger of a gun really hard and really fast, it doesn’t fire any faster or harder than if you just squeeze it gently. How could neurons be all or nothing when sensation is very graded? And the answer is although neurons are all or nothing, there are ways to code intensity. So one simple way to code intensity is the number of the neurons firing, the more neurons the more intense. Another way to increase intensity is the frequency of firing.Neurons are connected and they talk to one another. Neurons relate to one another chemically in a kind of interesting way. Between any neurons, between the axon of one neuron and the dendrite of another, there’s a tiny gap. The gap could be one ten-thousandth of a millimeter wide. This infinitesimal gap is known as a synapse. And what happens is when a neuron fires, an axon sends chemical shooting through the gap. These chemicals are known as neurotransmitters and they affected the dendrites.There are two sorts of ways you could fiddle with neurotransmitters and correspondingly two sorts of drugs. There are agonists. And what a agonist does is increases the effect of the neurotransmitters either by making more neurotransmitters or stopping the cleanup of the neurotransmitters or in some cases by faking a neurotransmitter, by mimicking its effects. Then there are antagonists that slow down the amount of neurotransmitters either because they destroy neurotransmitters or they make it hard to create more or in some cases they go to the dendrite of the neuron and they kind of put a paste over it so that the neurotransmitters can’t connect. And it’s through these clever ways that neurons can affect your mental life.For instance, there is a drug known as Curare, and Curare is an antagonist. It blocks motor neurons from affecting muscle fibers. What it does then is it paralyzesyou.Alcohol is inhibitory. It inhibits the inhibitory parts of your brain. If you take enough alcohol, it then goes down to inhibit the excitatory parts of your brain and then you fall on the floor and pass out.Amphetamines (安非他命) increase the amount of arousal, in particularly, they increase the amount of norepinephrine（肾上腺素），a neurotransmitter that’s responsible for just general arousal. Amphetamines include drugs like “speed” and “coke”.There are Prozac（百忧解）works on serotonin(血清素). And one problem is that “For depression” is that there’s too little a neurotransmitter known as serotonin. Prozac makes serotonin more prevalent and so in some extent might help alleviate depression.Parkinson’s disease is a disease involving destruction of motor control and loss of motor control, difficulty moving. And one factor in Parkinson’s is too little of neurotransmitter known as dopamine（多巴胺）。