a iso-intensity mural nodule on T2 ▪ Contrast enhancement with both CT and MRI
vermis
T1
T1-enhance
T2
F 62Y
Pathology
Diffuse astrocytoma-GradeⅡ
Grade-Ⅱ Diffuse astrocytoma
Classification and Diagnosis of astrocytoma(星形细胞瘤)
Lecturer: Guo Xiang
Morbidity of Astrocytoma
Astrocytic tumor 78%
Glioma Primary 40% brain tumor
Type of Astrocytoma
Imaging Characteristic
▪ Brainstem or supratentorial white matter
▪ poorly defined border
▪ Low-density on CT slightly>CSF
▪ No significant enhancement
F 54Y
Grade-Ⅲ Anaplastic astrocytoma
Grade-Ⅳ Glioblastoma
borderline tumor surgery
recur
malignancy will be higher
弥漫型星形细胞瘤属于交界性肿瘤， 容易复发，且恶性度有不断增加的趋 势，最终发展为胶质母细胞瘤。
▪ Because the treatment of astrocytoma is mainly based on pathological type ,so it will be very helpful to make an accurate diagnosis to the level of cells .
Anaplastic astrocytoma-GradeⅢ
the tumor enhanced distinctly
Glioblastoma-Grade-Ⅳ
T1
T2
FLAIR
T1-enhance
T1
▪ Adulthood Mixed density or signal lesion ▪ Hemorrhage and necrosis Contrast-enhance
=3:1)
subependymal nodules
Reddish-yellow pimples
红黄色丘疹
contrast-enhance hydrocephalus脑积水 favorable clinical outcome
M 16y T2
T1-enhance
T1
CT non-contrast
T1WI hypointensity signal T2WI hyperintensity signal
Cystic change
No or slightly enhancement
Surgical field and Specimen
The tumor showed diffusely infiltrated growing. NO hemorrhage and necrosis.
Pilocytic
Diffuse astrocytoma
astrocytoma
AND
Anaplastic
Ⅱ级 弥漫型星形细胞瘤
Ⅰ级 Subependymal 毛细胞型星形细 giant cell
astrocytoma
胞瘤、室管膜下 astrocytomas 巨细胞星形细胞
瘤
Ⅲ级
间变型
WHO
星形细 胞瘤
Pilocytic astrocytoma-GradeⅠ
▪ Children ▪ Cerebellum hemispheres or vermis ▪ Solid and cystic part ▪ Normal tissue>solid nodule>cystic mass>CSF
in density on NCCT ▪ MRI : a high-signal-intensity cyst surrounding
classification
Ⅳ级 胶质母细胞瘤
Ⅰ~Ⅳ
ndymal giant cell astrocytomas-GradeⅠ
epiloia（结节性硬化）
chromosomal 染色体疾病 disorder
8Y~18Y (male-to-female ratio