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骨关节炎、运动损伤与胶原蛋白

骨关节炎、运动损伤与胶原蛋白Osteoarthritis osteoarthritis, athletic injury and collogen骨关节炎Osteoarthritis骨关节炎(osteoarthritis)又名退行性骨关节炎,为关节软骨发生退行性变,并在关节边缘有骨刺形成。

骨关节炎多见于老年人,随着人类平均寿命的延长,骨关节炎的发病率愈来越高,它严重妨碍工作,成为50岁以后丧失劳动力的第二个常见原因。

The osteoarthritis other name recession osteoarthritis, has the degeneration for the articular cartilage, and has the spur formation in the joint edge. The osteoarthritis sees in the senior citizen, along with the human mean lifetime's extension, osteoarthritis's disease incidence rate comes to be higher, it hinders the work seriously, will become 50 year old of later disabled the second common reason.骨关节炎可分为原发性和继发性骨关节炎两大类,原发性主要为关节软骨的退行性老化病变,随着年龄的增长而日渐加重,软骨是所有结缔组织中老化现象较显著的组织,软骨老化是正常的生理演变,但可以在遗传的基础上因人而异,有的发生较早,比较快速,也有的发生较晚,较缓慢,一般病情进展与疲劳过度及关节负担过重有关。

继发性骨关节炎即先有其它疾病如先天性发育异常、外伤、骨骼的缺血坏死、下肢不等长及畸形等,而逐渐导致关节软骨的病变。

此外,骨关节炎还可能因不适当地长期大量激素及局部的放射线治疗所引起。

The osteoarthritis may divide into primary and the sequential osteoarthritis two broad headings, the primary stage mainly for articular cartilage's recession aging pathological change, along with age growth, but aggravates day after day, the cartilage is all knots contracts in the organization the ageing phenomenon remarkable organization, the cartilage aging is the normal physiological evolution, but may be different from person to person in the heredity foundation, some occurrences, are quite early fast, some occurrences are also late, is slow, generally the condition progress and weary excessively and the joint burden concerns overweight. The sequential osteoarthritis namely has other disease like congenitalness growth exceptionally, the flesh wound, skeleton's ischemia necrosis, the lower limb not to wait for long and abnormal and so on first, but causes articular cartilage's pathological change gradually. In addition, because the osteoarthritis also possible not suitably the long-term massive hormones and the partial radioactive rays treatment cause.肥胖患者关节负重增加,人体为维持重心会发生膝部的内翻畸形,使膝关节两侧间隙负重不平衡,导致退行性变,积累性的微小损伤可造成软骨下骨的硬化改变,影响关节软骨对关节负重的抵抗力,导致软骨的退变,上下楼梯滑一下看起来不重的损伤,能在很短的时间内传递给关节软骨过重的负荷。

The obese patient joint carries a heavy load increases, the human body will have knee's in for the maintenance center of gravity to turn abnormally, will cause the knee joint both sides gap to carry a heavy load not balanced, will cause the degeneration, the accumulation small damage to be possible to create under the cartilage bone's hardened change, will affect the articular cartilage the resistivity which will carry a heavy load to the joint, will cause the cartilage to draw back changes, the high and low staircase will slide looks like not the heavy damage, can give the articular cartilage overweight load in the very short time biography.性别与骨关节炎的发生也密切相关,女性在绝经前其骨关节炎的发生与男性相似,但到绝经期以后,女性骨关节炎的发生率明显高于男性。

特殊职业的人群中,其骨关节炎的发生率也较高,如矿工由于长期处于半蹲或蹲位,且需用肘关节,而引起膝、肘关节骨关节炎发生增加;我国广大农村地区,有些地区的农民需采摘棉花或工厂的纺织女工,其手关节骨关节炎也较常见。

The sex and osteoarthritis's occurrence closely is also related, the female its osteoarthritis's occurrence is similar before the menopause with the male, but after the menopause, the feminine osteoarthritis's formation rate is higher than the male obviously. In the special occupation's crowd, its osteoarthritis's formation rate is also high, like miner, because is in for a long time partly squats or squats the position, and needs the elbow joint, but causes the knee, the elbow joint osteoarthritis to occur increases; Our country general countryside area, some area's farmer must pick the cotton or the factory textile female worker, its articular arthritis is also common.当人体渐趋老化,或因创伤或疾病,关节软骨出现退化,逐渐出现断裂、失去弹性,随之发生裂缝、糜烂与溃疡,使软骨表面呈毛刷状,粗糙不堪。

不光滑的软骨面相互摩擦,使软骨损毁更进一步加重。

这时关节软骨的完整性就遭到破坏。

关节软骨基质分解和合成失调造成软骨的进一步破坏,软骨下骨板由于缺乏软骨的保护,局部受到异常的压力而发生代偿性增生(骨刺形成),严重影响人们的生活。

When the human body tends to be the aging, either because of the wound or disease, the articular cartilage presents the degeneration, presents the break, to lose the elasticity gradually, has the crack, the erosion and ulcer along with it, causes the cartilage table delivering in person hair brush shape, is unable to withstand roughly. Not the smooth cartilage surface rubs mutually, causes the cartilage damage further aggravation. By now articular cartilage's integrity was destructed. The articular cartilage matrix decomposition and synthesis being out of balance create cartilage's further destruction, under the cartilage the bone board, because lacks cartilage's protection, receives the unusual pressure to have the redemptive proliferation partially (spur to form), serious influence people's life.运动损伤Athletic injury现在,越来越多的人在运动和工作时出现关节强直和疼痛症状,尤其是运动员和老年人,即使有充分的营养和锻炼,仍然会发生一些软骨磨损和撕裂的情况。

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