Fibrosa
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9
Epithelium (non keratinized stratified squamous)
Tunica submucosa with glands
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10
ESOPHAGUS
Junction of esophagus and cardia
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11
STOMACH
Chief Parietal cell Mucous neck cell Enteroendocrine cell Gastric stem cell
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16
chief cell：zymogenic cell
Location: predominate in the lower of gastric gland LM: small than parietal cell, basophilic cytoplasm EM: have the characteristics of a protein synthesizing
Function: secreting pepsinogen which activated in acidic environment into pepsin.
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17
parietal cell ：oxyntic cell
Location: mainly in the upper half of gastric gland LM: round or pyramidal morphology and intensely
eosinophilic cytoplasm EM: intracellular canaliculus and abundance of
mitochondria
Function: secreting HCl and intrinsic factor
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18
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19
STOMACH: Cell types
(fibrosa or serosa)
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4
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5
TONGUE
Lower surface：smooth
mucous
Dorsal surface：irregular
Filiform papillae Fungiform papillae Circumvallate papillae
Taste bud
14
surface mucous cell
gastric pit--surface epithelia extent into lamina propria
Cardiac gland lamina propria Fundic gland
Pylorus gland
ppt课件15ຫໍສະໝຸດ Fundic gland ：
mucosa: epithelium, lamina propria, mucularis mucosae
gastric pit, gastric gland
submucosa
muscularis: smooth muscle
inner oblique, middle circular, outer longitudinal
muscularis：mass of striated skeletal muscular
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6
Filiform papillae
Fungiform papillae Foliate papillae
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7
taste buds
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8
ESOPHAGUS
stratified
squamous
submucosa
submucosal nerve plexus gland(only in esophagus and duodenum)
muscularis: inner circular, outer longitudinal
(skeletal or smooth muscular)
adventitia：thin loose connective tissue
} epithelium
lamina propria muscularis mucosae
Tunica mucosa
Tunica submucosa
Tunica muscularis
skeletal in upper 1/3rd
mixed in middle 1/3rd
smooth in lower 1/3rd
3
General structure of digestive tract
mucosa
epithelia lining: (stratified squamous or simple culumnar)
lamina propria: LCT(vessel, nerve, gland, LT)
muscularis mucosa: thin smooth macular
Mucous neck cells present in cluster or as single cells between parietal cells in the necks of gastric glands.
parietal cell/oxyntic cell Chief/Peptic cell
serosa: mesothelium
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12
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13
STOMACH: Divisions
Fundus
Cardia
Corpus
Pylorus
Histology shows corpus & fundus to be the same = “fundic stomach”
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Gastric stem cell few in number, these cells can differentiate into mucous neck, parietal, chief and enteroendocrin cells
胃肠道组织学
消化与营养
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1
Digestion & Nutrition
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2
教学目标及基本要求
1. 掌握消化管的基本结构。 2. 了解口腔粘膜的结构。 3. 了解舌的结构和牙的结构。 4. 掌握消化管各段的结构特点及功能。 5. 了解消化管的免疫功能。 6. 了解消化管内分泌功能。
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