汉恒在一系列基因载体技术如腺病毒、慢病毒、腺相关病毒、逆转录病毒、 细胞功能学服务的基础上，进一步开发基因及信号通路研究工具，包括自噬流 研究工具、lncRNA&环状RNA载体工具、分子载体探针、基于病毒载体的 Crispr/Cas9基因编辑工具等。
以核心基因技术为基础，汉恒更加注重技术应用与临床转化。
汉恒简史
2010成立 2012年 4年多的发展 短期目标
中期目标 2-5年内
长期目标 10年内
病毒载体为工具的基 因技术操作全平台
覆盖、并抢占国内主流科 研、临床前研究及药物研 发的AAV市场，完成基础 底层市场的教育及占领
上市1-2种自主知识产 权的基因治疗AAV药物
专注于基因技术的 研发与应用转化
--您身边的病毒载体专家
汉恒生物2017产品手册
目录
关于公司
01
汉恒简史 公司简介
02
汉恒客户 发表文献
06
一流质量标准 汉恒专利
07 公司优势
08 产品介绍
专题研究
25 悬浮细胞专用病毒
26 原代T细胞专用病毒
27 环状RNA专题研究
28 自噬专题研究
30 CRISPR-Cas9专题研究

32
探针工具 细胞器定位工具
特色服务
09 腺相关病毒AAV 14 光遗传学AAV现货工具 17 化学遗传学AAV现货工具 19 腺病毒 22 慢病毒 24 逆转录病毒
汉恒自主研发试剂
33 HB-infusionTM 无缝克隆试剂盒 34 LipoFiterTM脂质体转染试剂 36 SaveItTM 抗支原体试剂盒 37 Annexin V-FITC 细胞凋亡检测试剂盒
2017客户最新文献节选
1 Zhu Y, Di S, Hu W et al. A new flavonoid glycoside (APG) isolated from Clematis tangutica attenuates myocardial ischemia/reperfusion injury via activating PKCepsilon signaling. Biochim Biophys Acta 2017; 1863:701-711. 2 Zheng X, Chen W, Hou H et al. Ginsenoside 20(S)-Rg3 induced autophagy to inhibit migration and invasion of ovarian cancer. Biomed Pharmacother 2017; 85:620-626. 3 Zhao H, Xue Y, Guo Y, Sun Y, Liu D, Wang X. Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension. Int Immunopharmacol 2017; 42:115-121. 4 Yang Z, Hou Y, Hao T et al. A human proteome array approach to identifying key host proteins targeted by Toxoplasma kinase ROP18. Mol Cell Proteomics 2017. 5 Xu J, Zhang X, Wang H et al. HCRP1 downregulation promotes hepatocellular carcinoma cell migration and invasion through the induction of EGFR activation and epithelial-mesenchymal transition. Biomed Pharmacother 2017; 88:421-429. 6 Wang X, Fu Z, Chen Y, Liu L. Fas expression is downregulated in gastric cancer. Mol Med Rep 2017; 15:627-634. 7 Wang T, Wang P, Cao Z et al. Effects of BMP9 and pulsed electromagnetic fields on the proliferation and osteogenic differentiation of human periodontal ligament stem cells. Bioelectromagnetics 2017; 38:63-77. 8 Wang P, Wang Y, Tang W et al. Bone Morphogenetic Protein-9 Enhances Osteogenic Differentiation of Human Periodontal Ligament Stem Cells via the JNK Pathway. PLoS One 2017; 12:e0169123. 9 Li M, Yuan Y, Hu B, Wu L. Study on Lentivirus-Mediated ABCA7 Improves Neurocognitive Function and Related Mechanisms in the C57BL/6 Mouse Model of Alzheimer's Disease. J Mol Neurosci 2017. 10 Li C, Guo XD, Lei M et al. Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both Abeta and Tau pathologies. Acta Pharmacol Sin 2017; 38:9-28.
汉恒已成为国内生物医 药科研与研发领域最主 流的基因载体与基因技 术供应商
与国内临床机构合作申 报并实施基因治疗临床 前及临床研究项目
公司简介
汉恒生物成立于2010年，专注于基因技术的研发与应用转化。2012年，
汉恒建立了以病毒载体为工具的基因技术操作全平台，经过7年多的发展，汉恒 已成为国内生物医药科研与研发领域最主流的基因载体与基因技术供应商。
产 品 手 册
01
汉恒客户发表文献节选
1 Jiang JZ, Yang BH, Ji LL et al. Metabolic-induced cytotoxicity of diosbulbin B in CYP3A4-expressing cells. Toxicol In Vitro 2017; 38:59-66. 2 Hu J, Zhang L, Yang Y et al. Melatonin alleviates postinfarction cardiac remodeling and dysfunction by inhibiting Mst1. J Pineal Res 2017; 62. 3 Guo J, Qin W, Xing Q et al. TRIM33 is Essential for Osteoblast Proliferation and Differentiation via BMP Pathway. J Cell Physiol 2017. 4 Gao Y, Hou R, Fei Q et al. The Three-Herb Formula Shuang-Huang-Lian stabilizes mast cells through activation of mitochondrial calcium uniporter. Sci Rep 2017; 7:38736. 5 Feng D, Wang B, Wang L et al. Pre-ischemia melatonin treatment alleviated acute neuronal injury after ischemic stroke by inhibiting ER stress-dependent autophagy via PERK and IRE1 signalings. J Pineal Res 2017. 6 Dong W, Sun S, Cao X et al. Exposure to TNFalpha combined with TGFbeta induces carcinogenesis in vitro via NF-kappaB/Twist axis. Oncol Rep 2017. 7 Zue J, Zhu C. GW27-e1151 ABCG1 protects vascular endothelial cells against high glucose-induced oxidative stress through the Nrf2-dependent pathway. Journal of the American College of Cardiology 2016; 68:C42. 8 Zhu W, Xu J, Jiang C et al. Pristane induces autophagy in macrophages, promoting a STAT1-IRF1-TLR3 pathway and arthritis. Clinical Immunology 2016. 9 Zhu T, Yao Q, Wang W, Yao H, Chao J. iNOS induces vascular endothelial cell migration and apoptosis via autophagy in ischemia/reperfusion injury. Cellular Physiology and Biochemistr