福建医科大学2010级硕士研究生《医学文献检索与利用》综合实习报告检索课题题目（中、英文）立妥昔单抗在治疗套细胞淋巴瘤中的作用The role of rituximab in treatment of Mantle-cell Lymphoma研究生姓名高超学号 2101003220 学科专业血液病导师姓名王少元报告完成日期 2010年11月15日总成绩福建医科大学图书馆医学文献检索教研室2010年10月编制一、检索情况（一）中文医学文献检索工具1．光盘数据库（中文光盘数据库CBMdisc）光盘数据库名称中国生物医学文献数据库检索年限 2008-2010 检出篇数 5 检索途径基本检索检索式主题词=（缺省[智能]：套细胞淋巴瘤）and（缺省[智能]：利妥昔单抗）检出文献题录（只填写5条文献题录）[1]葛洪峰,段永建,李旭等.FCMR方案联合沙利度胺及局部放疗治疗难治复发套细胞淋巴瘤临床观察[J].中国医师进修杂志,2010,33(1)[2]李坚.套细胞淋巴瘤治疗进展[J].国际肿瘤学杂志,2009,36(5).[3]仲凯励.套细胞淋巴瘤靶向治疗进展[J].中华医学信息导报,2009,24(5)[4]杨秀明,马高尉.1例美罗华引起过敏反应的护理体会[J]. 中华现代护理学杂志 2008,5(19)[5]钟定荣(1),凌庆(1),关鸿志(2),李剑(3).中枢神经系统原发性套细胞淋巴瘤[J]中国现代神经疾病杂志 2008,8(1)数据库名称维普中文科技期刊数据库检索年限 2005-2010 检出篇数 17篇检索途径高级检索检索词关键词=美罗华+CD20单抗+利妥昔+靶向治疗*(套细胞淋巴瘤+恶性淋巴瘤)*(医药卫生)*全部期刊*年=2005-2011检出文献题录（只填写5条文献题录）[1] Habermann TM Weller EA Morrison VA.抗CD20单抗（Rituximab）作为B细胞淋巴瘤老龄患者初始治疗的新标准[J]癌症进展.2006,4(5).-376-376[2] 张小可,李梅君.套细胞淋巴瘤（MCL）治疗进展[J]中国社区医师：综合版.2008,10(17)[3] 黄晓燕. Biovest将套细胞淋巴瘤定为BiovaxID的第二适应症[J]国外药讯.2010(7)[4] 陆英, 华波.利妥昔联合沙利度胺对复发／难治的外套细胞淋巴瘤的抗瘤作用[英]／Hannes K…//Blood[J]国外医学：内科学分册.2005,32(5)[5] Habermann TM Weller EA Morrison VA.抗CD20单抗（Rituximab）作为B细胞淋巴瘤老龄患者初始治疗的新标准[J]癌症进展.2006,4(5)并选择你的导师的一篇论文进行引文分析（引用及被引用情况）。

数据库名称维普引文科技期刊数据库检索年限 1998-2010 检索途径传统检索检索词作者*机构=王少元*福建省血液病研究所检出文献题录张轶文,王少元.抑制性消减杂交筛选疾病相关基因的研究进展[J] 中华内科杂志.2005, 6（1）被引用文献题录（只填写1－2条文献题录）[1].刘静,赵颖.抑制性消减杂交（SSH）技术及其应用[J] 河北化工 2008[2].阳志军,杨光,蒋燕明,冉宇靓,杨治华,张玮,张洁清潘忠勉,李力.卵巢上皮性癌相关抗原的筛选和血清学检测[J] 中华妇产科杂志 2007（2）引用文献题录（只填写1－2条文献题录）[1].季明春陈红菊严华申厚凤.应用抑制性消减杂交技术分析淋球菌染色体介导的耐药相关核苷酸序列[J].中华微生物学和免疫学杂志,2003,23(5):388-392,.[2].陈忠斌杨静王华孙偶军王升启.应用抑制性消减杂交技术筛选流感病毒感染宿主应答基因[J].中国生物化学与分子生物学报,2003,19(2):156-161,.（二）外文医学文献检索工具1．外文光盘数据库（MEDLINE CD-ROM 、Ovid数据库中的MEDLINE或NCBI 数据库PubMed任选一种）数据库名称 NCBI 数据库PubMed检索年限 2008-2010 检出篇数 26篇检索途径 advanced seartch 检索式主题词= (mantle cell lymphoma) AND (treatment OR therapy) AND rutuximab 检出文献题录（只填写5条文献题录）1. Romaguera JE, Fayad LE, McLaughlin P, Pro B, Rodriguez A, Wang M, Weaver P, Hartig K,Kwak LW, Feldman T, Smith J, Ford P, Goldberg S, Pecora A, Goy A.Phase I trial of bortezomibin combination with rituximab-HyperCVAD alternating with rituximab, methotrexate andcytarabine for untreated aggressive mantle cell lymphoma.Br J Haematol. 2010Oct;151(1):47-53. doi: 10.1111/j.1365-2141.2010.08315.x. Epub 2010 Aug 5.2. Romaguera JE, Fayad LE, Feng L, Hartig K, Weaver P, Rodriguez MA, Hagemeister FB, ProB, McLaughlin P, Younes A, Samaniego F, Goy A, Cabanillas F, Kantarjian H, Kwak L, WangM.Ten-year follow-up after intense chemoimmunotherapy with Rituximab-HyperCVADalternating with Rituximab-high dose methotrexate/cytarabine (R-MA) and without stem cell transplantation in patients with untreated aggressive mantle cell lymphoma.Br J Haematol.2010 Jul;150(2):200-8. Epub 2010 May 26. Review. Erratum in: Br J Haematol.n 2010Oct;151(1):111.3. Ruan J, Martin P, Coleman M, Furman RR, Cheung K, Faye A, Elstrom R, Lachs M, HajjarKA, Leonard JP.Durable responses with the metronomic rituximab and thalidomide plus prednisone, etoposide, procarbazine, and cyclophosphamide regimen in elderly patients withrecurrent mantle cell lymphoma.Cancer. 2010 Jun 1;116(11):2655-64.4. Lossos IS, Hosein PJ, Morgensztern D, Coleman F, Escalón MP, Byrne G E Jr, RosenblattJD, Walker GR.High rate and prolonged duration of complete remissions induced by rituximab, methotrexate, doxorubicin, cyclophosphamide, vincristine, ifosfamide, etoposide,cytarabine, and thalidomide (R-MACLO-IVAM-T), a modification of the National CancerInstitute 89-C-41 regimen, in patients with newly diagnosed mantle cell lymphoma.Leuk Lymphoma. 2010 Mar;51(3):406-14.5. Pott C, Hoster E, Delfau-Larue MH, Beldjord K, Böttcher S, Asnafi V, Plonquet A, SiebertR, Callet-Bauchu E, Andersen N, van Dongen JJ, Klapper W, Berger F, Ribrag V, van Hoof AL,Trneny M, Walewski J, Dreger P, Unterhalt M, Hiddemann W, Kneba M, Kluin-Nelemans HC, HermineO, Macintyre E, Dreyling M.Molecular remission is an independent predictor of clinicaloutcome in patients with mantle cell lymphoma after combined immunochemotherapy: a EuropeanMCL intergroup study.Blood. 2010 Apr 22;115(16):3215-23. Epub 2009 Dec 23.2．外文全文期刊数据库（Ovid数据库、Springer在线期刊及EMCC任选一种）数据库名称西文生物医学期刊文献数据库（EMCC）检索年限 2000-2010 检出篇数 5篇检索途径复合检索检索词主题词=（mantle cell lymphoma） AND (therapy) 检出文献题录（只填写5条文献题录）1．Mangel J;Buckstein R;Imrie K;Spaner D;Crump M;Tompkins K;Reis M;Perez-OrdonezB;Deodhare S;Romans R;Pennell N;Robinson JB;Hewitt K;Richardson P;Lima A;PavlinP;Berinstein NL;Immunotherapy with rituximab following high-dose therapy and autologousstem-cell transplantation for mantle cell lymphoma.Semin Oncol. 2002V29N1 Suppl 2:56-692．Eve HE;Linch D;Qian W;Ross M;Seymour JF;Smith P;Stevens L;Rule SA;Toxicity offludarabine and cyclophosphamide with or without rituximab as initial therapy for patientswith previously untreated mantle cell lymphoma: results of a randomised phase II study.Leuk Lymphoma. 2009V50N2:211-53． Hsi ED;Jung SH;Lai R;Johnson JL;Cook JR;Jones D;Devos S;Cheson BD;Damon LE;Said J;Ki67and PIM1 expression predict outcome in mantle cell lymphoma treated with high dose therapy,stem cell transplantation and rituximab: a Cancer and Leukemia Group B 59909 correlativescience study.Leuk Lymphoma. 2008V49N11:2081-904． de Guibert S;Jaccard A;Bernard M;Turlure P;Bordessoule D;Lamy T;Rituximab and DHAPfollowed by intensive therapy with autologous stem-cell transplantation as first-linetherapy for mantle cell lymphoma.Haematologica. 2006V91N3:425-65． Thieblemont C;Antal D;Lacotte-Thierry L;Delwail V;Espinouse D;Michallet AS;TraulleC;Bouafia-Sauvy F;Giraud C;Salles G;Guilhot F;Coiffier B;Chemotherapy with rituximabfollowed by high-dose therapy and autologous stem cell transplantation in patients withmantle cell lymphoma.Cancer. 2005V104N7:1434-41（三）网络医学信息检索1．利用搜索引擎检索与本专业课题相关的网页（yahoo、 google or sohu 任选一种）检索工具名称 google 检索途径普通搜索检索记录数1,040,000只填写3条简要信息1中华血液病网血液病包括(白血病,儿童白血病,再障,MDS,骨髓瘤,血友病,地中海贫血,骨髓纤维化等分类) ；血液健康网主要针对这些常见血液病进行研究与治疗；.../2血液病疾病知识_血液病专家排行_咨询血液病专家_好大夫在线666篇血液病患友亲历的看病经验、404位大医院专家介绍血液病症状、血液病治疗方案等；各地血液病专家排行；直接向专家本人咨询。