Cover letter 写法一、什么是cover letter?The covering letter is a letter from the authors to the EditorProvide necessary information relevant to the manuscriptAdditional explanation from the authors二、为什么重要？An important opportunity to ‘sell’ your paperMS without a cover letter poses problems:To which journal?New MS or revised MS?MS misdirected by reviewers or editors?Whom to communicate if more than on authors?Write the correct address, including telephone, fax numbers, & e-mail, or possible reviewersBe kind to the editor and state why you have submitted that particular package三、如何写1.称谓Dear Dr. 主编name:2.The title of the manuscript, the numbers of tables, figures, charts, plates and so on;(1)This is a manuscript by**and **entitled “.......”. It is submitted to be considered for publication as a “...” in your journal.(2)We submit our manuscript entitled " 文章title" to 杂志名for publication.(3)On behalf of my co-authors, I am submitting the enclosed material “ TITLE ” for possible publication in JOURNAL.(4)We would like to submit the enclosed manuscript entitled " *** ", which we wish to be considered for publication in **journal.(5)Enclosed are a manuscript by sujian, y ang kun, chenzhihua．Su jian titled“Hypothermia after Acute Ischemic Stroke”．It is submitted to be considered for publication as a“review" in your journal．(6) Enclosed are two complete copies of a manuscript by Mary Q. Smith a nd John L. Jones titled “Fatty acid metabolism in Cedecianeteri,” which is being submitted for possible publication in the Physiology and Metabolism section of the Journal of Bacteriology.3.Some journals require the authors to briefly introduce his resea rch purposes, methods and results(接着简单介绍你文章的主要创新点和意义，不易过多，但要突出新意和关键点)(1) We believe the paper may be of particular interest to the readers of your journal as it ........(2)We believe that two aspects of this manuscript will make it interesting to general readers of **journal. First, ***.Second, ***.Further, ***.(3)We believe the paper may be of particular interest to the readers of your journal.4. The statement that this manucript has never been partly or wholely published in or submitted to any other journals;(1) The work described has not been submitted elsewhere for publication, in whole or in part, and all the authors listed have approved the manuscript that is enclosed.(2)This paper is new. Neither the entire paper nor any part of its content has been published or has beenaccepted elsewhere. It is not being submitted to any other journal.(3)I hereby certify that this paper consists of original, unpublished work which is not under consideration for publication elsewhere.(4)We certify that we have participated sufficiently in the work to take public responsibility for the appropriateness of the experimental design and method, and the collection, analy sis, and interpretation of the data.(5) Neither the entire paper nor any part of i ts content has been published or has been accepted elsewhere ．It is not being submitted to any other journal．(6) This MS is new, is not being considered elsewhere, and reports new findings that extend results we reported earlier in the Journal of Biological Chemistry (145: 112-117, 1992).5. The statement that all authors in the manuscript have agreed to submit it to this journal and it's better to have each one's signature;(1) All authors have seen the manuscript and approved to submit to y our journal.(2)We have reviewed the final version of the manuscript and approve it for publication. T o the best of our knowledge and belief, this manuscript has not been published in whole or in part nor is it being considered for publication elsewhere.6.The statement that the research in the manuscript has been conducted under the guidance of international ethical standards if the research uses animals as experimental materials;7.表达祝愿Thank you very much y our considering our manuscript for potential publication. I'm looking forward to hearing from you soon.8. The correspondence information of the correspondent;(1)Correspondence should be addressed to **at the following address, phone and fax number, and email address:(2)Correspondence and phone calls about the paper should be directed to Su jian at the following address，phone and fax number，and e-mail address：四、范文（1）Dear Dr. RichardI enclose a manuscript entitled The Preparation of the Monokaryon Protoplast and its Regeneration in Oyster Mushroom (Pleurotusostreatus), which I submit for possible publication in the Jounal of Biosource T echnology. All of the authors agree to the submission of this paper.The text includes 20 pages, 3 tables, and 2 figures prepared using Microsoft W ord Processing 2003 according to the journal's Instructions to Authors. We have provided all required supporting documentation.We respectfully submit that the following individuals would be suitable peer reviewers based on their expertise in the field:Li Y u, Microbiological Research Institute, Chinese Acadmey of Agricutlureal Sciences. E-mail: li_yu@y Zhang Jun, Resources and Environmental Protection School, Sichuan Agricultural University. E-mail:zhangjun@y Chen Wei, School of Horticulture, China Agricultural University. E-mail: chenwei@y In recent y ears, our research group has had some conflicts with Li Haha and Wang Chuachua in Sichuan Institute of Microbiology in project application. We request that these individuals not be consulted.We thank you for considering this work and look forward to y our response. Please direct all correspondence about this manuscript to me (or Dr. Zhang San, e-amil: Zhangsan@y ).SincerelyZhang Shane-mail: zhangsan@y The following are all the authors in this paper and their signature.Zhang San XXXLi Si XXXWang Wu XXXYang Yu XXX（2）Dear Editor,We would like to submit the enclosed manuscript entitled "GDNF Acutely Modulates Neuronal Excitability and A-type Potassium Channels in Midbrain Dopaminergic Neurons", which we wish to be considered for publication in Nature Neuroscience.GDNF has long been thought to be a potent neurotrophic factor for the survival of midbrain dopami nergic neurons, which are degenerated in Parkinson’s disease. In this paper, we report an unexpected, acute effect of GDNF on A-type potassium channels, leading to a potentiation of neuronal excitability, in the dopaminergic neurons in culture as well as in adult brain slices. Further, we show that GDNF regulates the K+ channels through a mechanism that involves activation of MAP kinase. Thus, this study has revealed, for the first time, an acute modulation of ion channels by GDNF. Our findings challenge the classic view of GDNF as a long-term survival factor for midbrain dopaminergic neurons, and suggest that the normal function of GDNF is to regulate neuronal excitability, and consequently dopamine release. These results may also have implications in the treatment of Parkinson’s disease.Due to a direct competition and conflict of interest, we request that Drs. XXX of Harvard Univ., and YY of Y ale Univ. not be considered as reviewers. With thanks for your consideration, I amSincerely y ours,（3）参考资料：复旦大学科技论文写作课程(卢宝荣) 网络资料整理人：GG。